K Ras Wild Type Colorectal Cancer. Also note that most of the regimens were evaluated on patients tested for KRAS mutations only. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a Tenesa A., Dunlop M.
Colorectal cancer (CRC) is the third most frequent type of cancer diagnosed and the second leading cause of cancer-related deaths Mutations in KRAS have been linked to CRC progression, with KRAS mutants having worse progression-free survival and overall.
Risk factors for colorectal Cancer. • Hereditary colon cancer syndromes • Inflammatory bowel disease • Personal history of CRC or adenomas • Family history of CRC • Aging • Dietary patterns Environmental factors Obesity / high caloric intake Red meat Fried.
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